Line a shallow baking pan (about 9 x 12 inches) with parchment paper.
In a large mixing bowl, combine 1/4 cup ketchup, egg, panko crumbs and onion.
Crumble beef over mixture and mix well.
On a large piece of waxed paper, pat beef mixture into a 10 x 6 inch rectangle. Spread remaining ketchup over meat to within 1/2 inch of sides and 1 1/2 inches of ends. Top with mustard and relish. Place four cheese slices on top; set aside remaining cheese.
Roll up the meat, jelly-roll style, starting with a short end and pulling away waxed paper while rolling. Seal seams and ends well. Place loaf, seam side down, on prepared baking pan.
Bake for 45 to 50 minutes. Slice reserved cheese in half diagonally; place on top of loaf and return to oven until cheese is melted.
Please note that some ingredients and brands may not be available in every store.
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